Publications

Learn more about our research and the science behind the PromarkerD test

Latest publications

Application of PromarkerD in Type 1

PromarkerD Demonstrates Benefit

PromarkerD Predicts Late-Stage Renal

Application of PromarkerD in Type 1 Diabetes

Davis T, et al. Application of a validated prognostic plasma protein biomarker test for renal decline in type 2 diabetes to type 1 diabetes: the Fremantle Diabetes Study Phase II. Journal of Clinical Diabetes and Endocrinology, 2024.

PromarkerD Demonstrates Benefit of Early Treatment with SGLT2-inhibitors

Peters KE, et al. Canagliflozin Attenuates PromarkerD Diabetic Kidney Disease Risk Prediction Scores. Journal of Clinical Medicine, 2023.

PromarkerD Predicts Late-Stage Renal Issues

Peters KE, et al. PromarkerD Predicts Late-Stage Renal Function Decline in Type 2 Diabetes in the Canagliflozin Cardiovascular Assessment Study (CANVAS). Poster presented at the American Diabetes Association’s 82nd Scientific Sessions, 2022.

Payer Budget Impact Study

Burchenal W, et al. Determination of Payer Budget Impact from Using an Innovative In Vitro Diagnostic in the Management of Diabetic Kidney Disease. Poster presented at Virtual ISPOR, 2021.

Economic Health Benefit Study

Burchenal W, et al. Demonstrating the Economic Health Benefit of using the PromarkerD In Vitro Diagnostic Test in the Prediction of Diabetic Kidney Disease. Poster presented at the American Diabetes Association’s 81st Scientific Sessions, 2021.

Drug Treatment Study

Peters KE, et al. Canagliflozin attenuates PromarkerD diabetic kidney disease risk prediction scores. Poster presented at the Australasian Diabetes Congress, 2021.

Clinical Utility Study

Fusfeld L, et al. Evaluation of the clinical utility of the PromarkerD in-vitro test in predicting diabetic kidney disease and rapid renal decline through a conjoint analysis. PLOS ONE, 2021.

PromarkerD vs Standard of Care

Peters KE, et al. A Comparison of PromarkerD to Standard of Care Tests for Predicting Renal Decline in Type 2 Diabetes. Poster presented at ASN Kidney Week, 2021.

Global Multi-Centre Prognostic Validation Study

Peters KE, et al. PromarkerD Predicts Renal Function Decline in Type 2 Diabetes in the Canagliflozin Cardiovascular Assessment Study (CANVAS) J Clin Med. 2020.

Multi-Site Assay Validation Study

Bringans SD, et al. A robust multiplex immunoaffinity mass spectrometry assay (PromarkerD) for clinical prediction of diabetic kidney disease. Clin Proteomics. 2020.

Cross-Platform Assay Validation Study

Bringans SD, et al. The New and the Old Platform Cross-Validation of Immunoaffinity Mass Spectrometry versus ELISA for PromarkerD, a Predictive Test for Diabetic Kidney Disease. Proteomes. 2020

Cross-Over Validation Study

Bringans SD, et al. PromarkerD as an immunoaffinity mass spectrometry assay for diabetic kidney disease. Poster presented at the 18th Human Proteome Organization World Congress. 2019

Cross-Platform Validation Study

Peters KE, et al. PromarkerD: A Novel Test for Predicting Rapid Decline in Renal Function in Type 2 Diabetes. Poster presented at the 18th Human Proteome Organization World Congress. 2019.

Biomarker Clinical Utility

Davis TME, et al. Apoptosis inhibitor of macrophage and diabetic kidney disease. Cell Mol Immunol. 2019.

Prognostic Validation Study

Peters KE, et al. Validation of a protein biomarker test for predicting renal decline in type 2 diabetes: The Fremantle Diabetes Study Phase II. J Diab Comp. 2019.

Diagnostic Study

Bringans SD, et al. Comprehensive mass spectrometry based biomarker discovery and validation platform as applied to diabetic kidney disease. EuPA Open Proteomics. 2017.

Prognostic Development Study

Peters KE, et al. Identification of Novel Circulating Biomarkers Predicting Rapid Decline in Renal Function in Type 2 Diabetes: The Fremantle Diabetes Study Phase II. Diabetes Care. 2017.

DKD assessment using biomarkers

US Patent – Methods of Assessing Diabetic Nephropathy Using CD5 Antigen-Like

AB SCIEX Technote

Protein Biomarker Research Pipeline for Developing Protein Biomarkers for Diabetic Kidney Disease.

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